Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Investigation of the Effect of Spinal Defects on Spondylolysis and Stress Fracture of Vertebral Bodies

M.S. Yeoman[1], C. Quah[2], A. Cizinauskas[1], K. Cooper[1], D. McNally[5], B. Boszczyk[2]
[1]Continuum Blue, Tredomen, Ystrad Mynach, United Kingdom
[2]The Centre for Spinal Studies and Surgery, Queen’s Medical Centre, Nottingham, United Kingdom
[5]Bioengineering Research Group, Faculty of Engineering, The University of Nottingham, Nottingham, United Kingdom

Spondylolysis (SL) is a defect of the spinal vertebra, and is typically caused by stress fracture of the pars interarticularis bone of the vertebral arch. It is especially common in adolescents who over train in sporting activities. Spina bifida occulta (SBO) is a malformation of the spine where the protruding vertebral bodies are not fully formed. In this study we demonstrate the predisposition ...

Analyzing Drug Delivery and Osteoblast Growth on a Porous Scaffold in a Perfusion Bioreactor

A. Sun, and S. Murray
Dept. of Biomedical Engineering
UCLA, Los Angeles, CA

Implantable Collagen sponges are used in Spinal Surgery as Drug Delivery Scaffolds. An optimal concentration of growth factor that strikes a balance between bone growth and adverse diffusion effects is difficult to find. The porous sponge also serves as a scaffold for Osteoblast growth, and fluid shear has been shown to mediate biological effects on that cell type. We use COMSOL Multiphysics ...

Modeling Phytoremediation by Mangroves

O. Richter[1], H. Anh Nguyen[1], V. Phuoc Nguyen[2]
[1]Institute of Geoecology, University of Technology Braunschweig, Germany
[2]Institute for Environment & Resources, HCM-City, Vietnam

Metal contaminants and organic pollutants are affecting aquatic environments in urban and industrial zones. Mangrove trees are capable of absorbing metal ions and organic pollutants. To estimate the remediation potential, a two dimensional model of water and substance flow in the soil plant system based on porous media equations was set up. We show that multiphysics approaches also apply to ...

Modeling Neural Tissue and Membrane Behavior During Far-field Current Injection

R. Sadleir[1], A. Minhas[2], and E.J. Woo[2]
[1]University of Florida, Gainesville, FL, USA
[2]Kyung Hee University, Seoul, Republic of Korea

In an earlier work we developed a finite element bidomain model of an aplysia abdominal ganglion in order to estimate the sensitivity of this contrast mechanism to changes in cell membrane conductance occurring during a gill-withdrawal reflex. We used our model to determine both current density and magnetic potential distributions within a sample chamber containing an isolated ganglion when it ...

Coupled PDEs with Initial Solution from Data in COMSOL Multiphysics®

M. K. Gobbert[1], X. Huang[1], S. Khuvis[1], S. Askarian[1], B. E. Peercy[1]
[1]University of Maryland - Baltimore County, Baltimore, MD, USA

This paper presents information on techniques needed in COMSOL Multiphysics® to enable computational studies of coupled systems of PDEs for time-dependent non-linear problems. Furthermore, we demonstrate how to use data files as input for initial conditions. To illustrate the techniques, we consider a system of two time-dependent non-linear PDEs from mathematical biology that couples an ...

A Comparison Between an A-V and V Formulation in Transcranial Magnetic Stimulation

B. Granula[1], K. Porzig[2], H. Toepfer[2], M. Gacanovic[1]
[1]University of Banja Luka, Banja Luka, Bosnia-Herzegovina
[2]Technische Universität Ilmenau, Ilmenau, Germany

The prediction of the exact location and intensity of the electric field induced in the human brain during Transcranial magnetic stimulation is a nontrivial computational task. Numerical simulations of the procedure can be used to acquire first approximations in a safe and controlled environment. In order to make this approach more accessible, it is necessary to reduce computation time as much ...

Material Characterization Method Development: From Education to Design Optimization

C. Morgan[1], N. Kenkare[1], M. Williams[2], A. Peterson[2], and D. Williams[2]
[1]Alcon Eye Care Division of Novartis R&D, Duluth, GA
[2]Alcon Eye Care Division of Novartis R&D and Georgia Institute of Technology Co-op Program, GA

Introduction of silicone hydrogel contact lens materials provided products of unprecedented capability to deliver oxygen to the eye during wear. One additional material characteristic of interest is the material’s permeability to ions. This paper discusses descriptive tools and optimization of an impedance method of characterizing ion permeability. A physical model of conductive paper with ...

Models for Simulation Based Selection of 3D Multilayered Graphene Biosensors

E. Lacatus [1], G. C. Alecu [1], A. Tudor [1],
[1] Politehnica University of Bucharest, București, Romania

At the forefront of a new generation of sensors graphene and graphene composite materials are intensively studied for medical and biosensing applications. The outstanding electrical, mechanical and quantum properties of graphene make them a promising material solution to overlap the existing gap between biological and non-biological systems into a continuum like-viscoelastic integrated model. ...

Modeling the Behavior of Phased Arrays in Brain Tissue: Application to Deep Brain Stimulation

V. Valente[1], A. Demosthenous[1], and R. Bayford[2]

[1]Department of Electronic & Electrical Engineering, University College London, London, United Kingdom
[2]Department of Natural Sciences, Middlesex University, London, United Kingdom

Deep Brain Stimulation (DBS) is a therapeutic tool used for a number of neurological disorders including chronic pain, incontinence and movement disorders, such as Parkinson’s disease. DBS consists of the low-frequency stimulation of an area of the brain, known as basal ganglia. The stimulation is provided by clinical implant, consisting of a pulse generator and an electrode lead ...

A Practical Method to Model Complex Three-Dimensional Geometries with Non-Uniform Material Properties Using Image-based Design and COMSOL Multiphysics®

J. Cepeda[1], S. Birla[2], J. Subbiah[2], H. Thippareddi[1]
[1]Department of Food Science & Technology, University of Nebraska, Lincoln, NE, USA
[2]Department of Biological Systems Engineering, University of Nebraska, Lincoln, NE, USA

Geometries with heterogeneous material properties are typically defined as a set of multiple parts, each part representing a different material. However, assembling or defining the individual parts of complex geometries can be difficult. A practical method based on image-based mesh generation, a custom algorithm for labeling materials, and interpolation functions of COMSOL Multiphysics® can be ...

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