Technical Papers and Presentations

Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

An Elastic and Hyperelastic Material Model of Joint Cartilage - Calculation of the Pressure Dependent Material Stress in Joint Cartilage

T. Reuter, and M. Hoffmann
fzmb GmbH
Research Centre of Medical Technology and Biotechnology
Bad Langensalza, Germany

In this paper we introduce a elastic and hyperelastic model to describe the pressure dependent material stress in joint cartilage. We used the pressure dependent E-modulus E = f(s) to calculate the material stress. E = f(s) is a degree 4 polynomial . The indentor was pressed 0.4 mm into the tissue. The results show that the maximal stress at the contact zone between indentor and cartilage account ...

A Multiphysics Approach to the Modeling of Biological Prosthetic Heart Valves

A. Avanzini[1], D. Battini[1], M. Berardi[1]
[1]UniversitĂ  degli Studi di Brescia, Brescia, Italy

The complex behavior of biological prosthetic heart valves was simulated. A multiphysics computational approach was adopted using different modules of COMSOL Multiphysics: the LiveLink(TM) interface was used to exchange the valve geometry with CAD, Structural Mechanics Module to set loads, boundary conditions and implement anisotropic hyper-elastic constitutive laws for leaflet tissue, PDE to ...

Biofluid-Structural Interaction in Abdominal Aortic Aneurysm for Predicting Timeline to Rupture: The Effect of Hypertension and Aorta Wall Material Properties

K. Cluff[1], H. Mehraein[1], G. Jayakumar[2]
[1]Bioengineering, Wichita State University, Wichita, KS, USA
[2]Industrial & Manufacturing Engineering, Wichita State University, Wichita, KS, USA

An abdominal aortic aneurysm (AAA) is a bulge formed in the large blood vessels that supply blood to the abdomen, pelvis, and legs. A fluid structure interaction model was developed in a 3D aortic aneurysm model, which was constructed from abdominal CT scan images. Combining medical imaging and computational fluid dynamics (CFD) in a time dependent study allowed the determination of wall ...

Microwave Exposure System for In Vitro and In Vivo Studies

C. Nadovich[1, 2], W. D. Jemison[2], J. A. Stoute[3], C. Spadafora[4]
[1]Lafayette College, Easton, PA, USA
[2]Clarkson University, Potsdam, NY, USA
[3]Pennsylvania State University, Hershey, PA, USA
[4]INDICASAT AIP, Ciudad del Saber, Panama

A computer controlled microwave exposure system and specialized applicators were constructed for the purpose of facilitating accurate observations of microwave radiation effects on uninfected and infected biological tissue in vitro and in vivo under different electromagnetic modalities and exposure configuration. To address diverse requirements, three different applicators were developed: a ...

Multiscale Model of Human Pathogen Growth on Fresh Produce

A. Warning[1], A. K. Datta[1]
[1]Department of Biological & Environmental Engineering, Cornell University, Ithaca, NY, USA

Predictive food microbiology currently first requires experimental data for growth on fresh produce and then fitting an empirical or semi-empirical model to the data, making extrapolation to other conditions (temperature, type of produce) difficult. Herein, we develop a mechanistic model for the growth of human pathogenic bacteria (Escherichia coli O157:H7 and Salmonella spp.) on spinach using ...

Design of a Cylindrical Photobioreactor with Central Orifice for the Production of Microalgae

N. N. V. Ramirez[1], L. M. Raymundo[1], J. O. Trierweiler[1]
[1]Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil

It is desired to design a photobioreactor for the production of voluminous samples of microalgae for lipid quantification. The reactor should provide good growing conditions even with periodic withdrawal of samples. It also should be compact for better use of laboratory space. Therefore, a photobioreactor with concentric tubes was modeled to verify the circulation of the culture medium. The ...

Hemodynamic Therapy of Middle Cerebral Artery Vasospasm Guided by a Multiphase Model of Oxygen Transport

S. Conrad[1,2], P. Chittiboina[3], and B. Guthikonda[3]

[1]Department of Bioinformatics and Computational Biology, Louisiana State University Health Sciences Center, Shreveport, LA, USA
[2]Department of Biomedical Engineering, Louisiana Tech University, Ruston, LA, USA
[3]Department of Neurosurgery, Louisiana State University Health Sciences Center, Shreveport, LA, USA

Cerebral vasospasm is a complication of subarachnoid hemorrhage and other neurosurgical emergencies that reduce blood flow to the brain. Part of the approach to management of vasospasm is to improve flow through the stenotic areas by reducing by decreasing blood viscosity and enhancing flow through the stenosis. To examine the interaction of these factors, we applied computational fluid dynamics ...

Evaluation of Performance of Enzymatic Biofuel Cells with Microelectrode Arrays Inside a Blood Artery via Finite Element Approach

C. Wang[1], Y. Song[1]
[1]Florida International University, Miami, FL, USA

Enzymatic biofuel cells (EBFCs) are considered as a promising candidate for powering miniature implantable devices. In order to predict the performance in the human blood artery, we simulated a 3D EBFC chip with highly dense micro-electrode arrays. In this simulation using COMSOL Multiphysics®, we applied the 1) Michaelis Menten equation; 2) Nernst potential equation; 3) Navier Strokes velocity, ...

Modeling Controlled Release of Actives from Structured Foods

A. D. Haydock, J. Melrose, P. Rayment, M. F. Butler, and G. Lian
Unilever R&D Colworth, Colworth House, Sharnbrook Bedford, UK

In this presentation, we describe the use of COMSOL for modeling release of active molecules from hydrogels as a model system of structured foods. We first discuss the structural changes of hydrogel in the gastro-intestinal (GI) tract environment and how this is modelled mathematically. We then discuss how to implement the mathematical equations in COMSOL. Computer simulations have been performed ...

Modelling the Coupled Heat and Mass Transfer during Fires in Stored Biomass, Coal and Recycling Deposits

F. Ferrero
Federal Institute for Materials Research and Testing Division II.2, Berlin, Germany

It is known that in big storages of bulk materials the danger of the self-ignition is relevant (long time storages). The Consequences of uncontrolled fires include considerable CO2 emission and economical and human losses to mention a few. The understanding of this phenomena is therefore of great importance.A numerical model can be of great help in understanding such complex phenomena. In this ...

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