N. M. Sundaram, M. Sneha, A. Kandaswamy, R. Nithya
PSG College of Technology, Coimbatore, Tamil Nadu, India
Dr. N.G.P. Institute of Technology, Coimbatore, Tamil Nadu, India
The majority of elderly patients are subjected to hip bone replacement due to dislocation of bone, mechanical failure and infection. The life time of the implant varies from patient to patient depending on their daily physical activity. Once the implant fails, re-operation of hip bone replacement is performed. In United States, there are approximately 18 revision hip replacements performed for ...
G. Megali, D. Pellicanò, M. Cacciola, F. Calarco, D. De Carlo, F. Laganà, and F.C. Morabito
DIMET Department, Faculty of Engineering, University “Mediterranea” of Reggio Calabria, Reggio Calabria, Italy
Constitutive properties of living cells are able to withstand physiological environment as well as mechanical stimuli occurring within and outside the body. We examined fluid flow and Neo-Hookean deformation related to the rolling effect. A mechanical model to describe the cellular adhesion with detachment is here proposed. We developed a finite element analysis, simulating blood cells attached ...
A. Altamirano, C. Toledo, A. Vera, R. Muñoz, and L. Leija
Centro de Investigacion y Estudios Avanzados
Instituto Politecnico Nacional
In this article, the aim is to study different types and forms of electromyography (EMG) electrodes, for bipolar configuration, and the electric interface with muscle phantom. COMSOL Multiphysics allows modeling shapes and contact surfaces. Surface and needle electrodes will be modeled. A number of different trials and combinations will be presented; exploring different geometric shapes and ...
An Assessment of the Suitability of the Body and Adult Head Coils for Transmission during Paediatric Magnetic Resonance Imaging
G.R. Cook, M.J. Graves, F.J. Robb, D.J. Lomas
Department of Radiology, University of Cambridge, Cambridge, United Kingdom
General Electric Healthcare Coils, Aurora, Ohio, USA
MRI offers many advantages over other modalities and its lack of ionizing radiation is important for children, but can be limited by the radio-frequency (RF) coils available. This work calculates Specific Absorption Rate (SAR) and homogeneity of the RF transmit field (B1+) when imaging infants in adult coils. Two birdcage-type coils were loaded by a tissue model and their B1+ homogeneities ...
N. P. Uth , J. Mueller , B. Smucker , A. Yousefi ,
 Department of Chemical, Paper, and Biomedical Engineering, Miami University, Oxford, OH, USA
 Research Computing Support, Miami University, Oxford, OH, USA
 Department of Statistics, Miami University, Oxford, OH, USA
Introduction: Bone tissue has a limited ability for regeneration; critically sized defects cannot self-heal and require medical intervention. Bone tissue engineering (TE) circumvents this issue by growing replacement bone tissue from the patient’s own cells inside scaffolds. TE scaffolds are porous constructs that act as a support structure during bone regeneration and helps cells attach and ...
G. Zhang [1, 2, 3],
 Department of Bioengineering, Clemson University, Clemson, SC, USA
 Department of Electrical and Computer Engineering, Clemson, SC, USA
 Institute for Biological Interfaces of Engineering, Clemson University, Clemson, SC, USA
Implant devices are assistive devices surgically placed in the human body to restore the functionality of organs and tissues. Metallic implants are often used for load bearing applications including the hip and knee joints. To allow maximum flexibility during surgery for surgeons to pick and choose different combinations of parts (say, head, neck and stem, in the case of total hip replacement), ...
Passive and Active Deformation Processes of 3D Fibre-Reinforced Caricatures of Cardiovascular Tissues
A. Di Carlo, P. Nardinocchi, T. Svaton, and L. Teresi
Modelling and Simulation Lab, Università Roma Tre, Roma, Italy
Dept. of Structural & Geotechnical Engineering, Università di Roma La Sapienza, Roma, Italy
Dept. of Mathematics, University of West Bohemia, Pilsen, Czech Republic
In this paper, we present a mathematical model of contractile elastic solids meant to simulate various districts of the cardiovascular system, and based on the concepts of active deformation and embedded muscle fibres. Specifically, here we deal with the modeling of the gross mechanics of the Left Ventricle (LV) which is strictly related to its pump function. As is well known, the effectiveness ...
S. Mackintosh, J. Rodgers, S.P. Blythe
Lifescan Scotland, Inverness, Scotland
This paper describes the modeling of a blood glucose sensor using COMSOL Multiphysics. Chemical species interaction and diffusion, coupled with electrochemical oxidation of multiple blood species produced a powerful working model used in developing and refining a range of blood glucose sensors for the commercial market.
Lowering of the Interstitial Fluid Pressure as a Result of Tissue Compliance Changes during High Intensity Focused Ultrasound Exposure: Insights from a Numerical Model
E. Sassaroli, B. O'Neill 
The Methodist Hospital Research Institute, Houston, TX, USA
Interstitial fluid pressure (IFP) is elevated in tumors. Owing to this elevated IFP, the interstitial fluid velocity (IFV) is negligible throughout the tumor but significant near the tumor margin. Any therapeutic strategy that can lower IFP will improve drug convection within the tumor and decrease convection of drugs from the tumor margin. High intensity focused ultrasound (HIFU) has been shown ...
E. Hollander, E. O. Kamenetskii, R. Shavit
Microwave Magnetic Laboratory, Department of Electrical and Computer Engineering, Ben Gurion University of the Negev, Beer Sheva, Israel
Microwave sensing and monitoring is very attractive for biological applications because of their sensitivity to water and dielectric contrast. Direct detection of biological structures in microwave frequencies and understanding of the molecular mechanisms of microwave effects is considered as a problem of a great importance. Nowadays, however, microwave technique for localized testing biological ...